-#if defined (__WXMAC__)
-# if ( !defined(__MACH__) || ( defined(__BIG_ENDIAN__) && __BIG_ENDIAN__ ) )
-# define WORDS_BIGENDIAN 1
-# else
-# undef WORDS_BIGENDIAN
-# endif
+/*
+ Handle Darwin gcc universal compilation. Don't do this in an Apple-
+ specific case since no sane compiler should be defining either
+ __BIG_ENDIAN__ or __LITTLE_ENDIAN__ unless it really is generating
+ code that will be hosted on a machine with the appropriate endianness.
+ If a compiler defines neither, assume the user or configure set
+ WORDS_BIGENDIAN appropriately.
+ */
+#if defined(__BIG_ENDIAN__)
+# undef WORDS_BIGENDIAN
+# define WORDS_BIGENDIAN 1
+#elif defined(__LITTLE_ENDIAN__)
+# undef WORDS_BIGENDIAN
+#elif defined(__WXMAC__) && !defined(WORDS_BIGENDIAN)
+/* According to Stefan even ancient Mac compilers defined __BIG_ENDIAN__ */
+# warning "Compiling wxMac with probably wrong endianness"